More than 90 companies have gone public, up from 81 in 2020 and 49 in 2019, according to SVB Leerink analysts. This was swiftly followed by another $300 million investment round in November 2021. Insights about top trending companies, startups, investments and M&A activities, notable investors of these companies, their management team, and recent To learn more about these VC firms and their 2021 investments take a look at their Crunchbase profiles: Stay up to date with recent funding rounds, acquisitions, and more with the 9 See announcement on the firms blog, http://indexventures.com/news-room/blog/our-new-fund-for-building-iconic-businesses The firm prefers to make investments in the workplace, healthcare and wellness, retail and marketplace software companies across Texas and other non-coastal regions. Largest investment: 13.6 million shares of Recursion Pharmaceuticals worth $245.1 million at the time of its IPO, Total holding value of 2021 IPOs: $473.5 million. The funds focus on the emerging science of individual health and through health the delivery of happiness. WebWith a total of USD 9.2bn, the oncology sector received the highest funding volume, followed by central nervous system (USD 6.0bn) and infectious diseases (USD 2.2bn). CEO: Andrew Sheiner. Blume Ventures Blume Ventures is an early-stage and seed-stage venture fund that has its headquarters in Mumbai, Maharashtra, India. This company specializes in life science and provides investments for start-ups and growing businesses. However, as the COVID Biotechnology boom ends, it is becoming more challenging for entrepreneurs to get venture money. Founded in 2014, Equinvest is comprised of entrepreneurs and senior managers.. . The Indian startup/ VC ecosystem will truly come of age City (cities) where offices are located: Boston; San Francisco; London, Fund size and status: Approximately $1.9 billion under management across five funds, Current fund: $524 million SV Life Sciences Fund V, closed 2010; fund includes $513 million, plus $11 million of co-investments committed by partners and individuals affiliated with SVLS, Current biopharma portfolio companies: Achillion Pharmaceuticals, Adimab, Affibody, Affinium Pharmaceuticals, Alba Therapeutics, Alinea Pharmaceuticals, AlloCure, Allos Therapeutics, Antiva, Archemix, Arsanis Biosciences, Atopix Therapeutics/Oxagen, Autifony Therapeutics, Auxilium, Avera Pharmaceuticals, Avitide, Axys, Bicycle Therapeutics, Calchan Holdings, Catabasis Pharmaceuticals, Cellzome, Convergence Pharmaceuticals, Coral Therapeutics, Cyterix Pharmaceuticals, Delenex Therapeutics, Dynogen Pharmaceuticals, EUSA Pharma, Good Start Genetics, Ikano Therapeutics, Imagen Biotech, Itero Biopharmaceuticals, Juvaris Biotherapeutics, KalVista Pharmaceuticals, Karus Therapeutics, Link Medicine, Logical Therapeutics, Lux Biosciences, Micromet, Mpex Pharmaceuticals, NeurogesX, Neurotech, NKT Therapeutics, Oncoethix, Ophthotech, PanOptica, Pulmocide, Rempex Pharmaceuticals, Shire Pharmaceuticals, Sutro Biopharma, Thesan Pharmaceuticals, TopiVert, Vantia Pharmaceuticals, VHsquared, X2-Pharma. Largest investment: 16.2 million shares of Graphite Bio worth $276 million at the time of its IPO, Total holding value of 2021 IPOs: $846 million. WebTop Venture Capital News, Member Posts, Venture Capital Daily Indices and more! Largest investment: 44 million shares of Sana Biotechnology worth $1.1 billion at the time of its IPO, Total holding value of 2021 IPOs: $1.9 billion. Healthcare, Security Services (B2B), Social Content, Software, Buyout/LBO, Debt General, Early Stage VC, Later Stage VC, PE Growth/Expansion, Recapitalization, Seed Round. Healthtech and biotech has consistently been a top sector for the destination of venture capital in recent years. The firm invests in disruptive and emerging B2B software, APIs, applications, frontier tech and marketplaces across a number of industries including supply chain, FinTech and workforce efficiency. Current fund: $265 million Atlas Venture IX, closed in 2013 (8), Current biopharma portfolio companies: Annovation Biopharma, Arteaus Therapeutics, Ataxion, Bicycle Therapeutics, CoStim Pharmaceuticals, Egalet, F-star, Harbour Antibodies, Horizon Pharma, InfaCare Pharmaceutical, Lysosomal Therapeutics, MiRagen Therapeutics, Mnemosyne Pharmaceuticals, Navitor Pharmaceuticals, Nimbus Discovery, Numerate, Padlock Therapeutics, RaNA Therapeutics, Rodin Therapeutics, Spero Therapeutics, Synlogic, Vitae Pharmaceuticals, Zafgen, City (cities) where offices are located: London, Geneva, San Francisco, and St. Helier, Jersey, Fund size and status: $3.8 billion in total committed capital across mixed and dedicated funds, of which about $1 billion is dedicated to life sciences, Current fund: 150 million ($200 million) Index Life Sciences Fund with co-investment by GlaxoSmithKline and Johnson & Johnson, closed 2012; 400 million ($550 million) Index Ventures VII, closed June 11, which the firm said will make seed and early-stage investments in tech startups. The top 10 biotech IPOs of 2021 | Fierce Biotech. Over the years, Boston has steadily built a tech hub that rivals other cities in the country. 8 Firm has disclosed on its website that it will soon split into two firms focused on technology and life sciences early stage investing. The life-sci firm will retain the Atlas brand, and plans to raise a new fund next year that would be similar in size to the $265 million Atlas raised for its ninth fund, Fortune reported on Oct. 2. Largest investment: 53.8 million shares of LianBio worth $861 million at the time of its IPO, Total holding value of 2021 IPOs: $1.2 billion. 4 On July 1, the firm submitted a Form D stating that its partners had raised $221.5 million toward a planned ninth fund of $750 million, to be named Esssex Woodlands Fund IX. In addition to an increased focus on algorithm engineering and digital health technologies, Third Rock Ventures has a history of investing in the Biotechnology sector. Biotech. Despite the venture boom, fundraising by new niche VCs in America has fallen from a peak of $14bn in 2018 to an expected $5.5bn in 2021. Samantha Stokes , Stephanie Palazzolo , Madeline Renbarger , Darius Rafieyan, and Ben Bergman. That seventh fund closed $50 million higher than the $400 million offering amount that the firm stated back on June 17, when it disclosed its plan to raise the fund in a Form D filing with the U.S. Securities and Exchange Commission. VC investment in the biopharma space is likely to surpass $20 billion in 2021, driven by the need to fund trials and build out research and development programs, as clinical trials resume and elective procedures restart. Apparel and Accessories, Beverages, Consumer Durables, Food Products, Healthcare, Other Restaurants, Hotels and Leisure, Services (Non-Financial), Software, Co-founders and General Partners Genevieve Gilbreath and Dan Graham. The lead investor often acts as the liaison between the startups founder(s) and the other participating investors, or is implicitly trusted by other investors to find the best terms for everyone. 10 Figure calculated based on adding the value of the new $450 million fund with the $3.5 billion previously disclosed by the firm. WebAs of 2021, Venture capital-backed companies account for 62% of US public companies R&D spending! Bridge, Convertible Debt, Early Stage VC, Seed Round. Founded in 2014, ATX Venture Partners is a US-based venture capital firm that focuses on seed, series A and early-stage B2B software investments, usually with a Texas-centric geographic focus. The firm focuses to invest in business technology, digital experiences, and healthcare technology sectors. OrbiMed and Fidelity Management and Research Co., however, participated in Adagios Series A, B and C rounds. RA Capital Management and OrbiMed led the way in both total dollars invested and the number of venture capital funding rounds led in the biotech industry last yearthe only two firms to make it onto both lists. Copyright 2023 Genetic Engineering & Biotechnology News. Current biopharma portfolio companies: Achaogen, Alcresta, Allena Pharmaceuticals, Amicus Therapeutics, Anaptys, Attercor, Cadence Pharmaceuticals, The Legal 500; Europe, Middle East & Africa . Largest investment: 11.9 million shares of Century Therapeutics worth $238.5 million at the time of its IPO, Total holding value of 2021 IPOs: $416.6 million. Fierce Biotech. Here is a breakdown of some of those leaders, based on Crunchbase data. In 1999, Novo Nordisk and Novozymes partnered to form Novo Ventures (Nova A/S), a Danish private limited venture capital firm headquartered in Hellerup, Denmark. The report predicts venture capital (VC) activity and performance for next year. Medtech. The biotech market has set a record for the number of initial public offerings in 2021. The center of it all is biotechnology, with over 430 biotech companies. 14On June 27, KPCB submitted Form D filings with the U.S. Securities and Exchange Commission disclosing plans to raise an early-stage growth fund of $450 million, known as KPCB XVI, as well as a later-stage fund of $750 million known as KPCB Digital Growth. The firms themselves are the sources of much of the information, though in some instances, amounts of capital under management were calculated by adding the value of newly closed funds with previously disclosed amounts. According to its website, the business has 36 IPOS and $3.2 billion under control. See: https://www.sec.gov/Archives/edgar/data/1602264/000160226414000001/xslFormDX01/primary_doc.xml Largest investment: 34.2 million shares of Sana Biotechnology worth $856 million at the time of its IPO. OrbiMed and. Several firms have already raised new funds and laid out investment plans for next year. Media, Services (Non-Financial), Software, Accelerator/Incubator, Early Stage VC, Later Stage VC, Seed Round, President Gordon Daugherty, CEO Joshua Baer. Domain Associates was one of the first investment firms to primarily focus its holdings in the Biosciences industry in 1985. After all, you cannot rush your way into building long-term relationships! MicroVentures is an online equity crowdfunding platform enabling angel investors to connect with startups to raise capital. PitchBook has published its 2021 U.S. Venture Capital Outlook report. 13 Includes all companies denoted on firms website as recent ventures in the life sciences focus area, within the Diagnostics and Therapeutics categories. Flagship, based in Cambridge, Massachusetts, is more of a venture-creation firm than a traditional VC it often creates the companies it invests in. These VC firms led the most funding rounds for biotech startups this year between Jan. 1 and Dec. 1, according to Crunchbase data. Flagship CEO Noubar Afeyan previously told Insider about the four-step creation process behind the firm's companies. Exclusive analysis of biotech, pharma, and the life sciences, https://reports.statnews.com/products/2021-ranking-biotechs-top-venture-capital-firms?utm_source=statnews.com&utm_medium=referral&utm_campaign=stat_reports_articlewidget2.0&utm_content=0621sub-header1, Reporting from the frontiers of health and medicine, You've been selected! Its biggest success, Moderna, has vaulted Flagship into biotech's top ranks with its COVID-19 vaccine. Texas Halo Fund is an investment firm based in Houston, Texas. Eighteen firms held shares worth $400 million or more in biotech companies that went public this year. The firm seeks to invest in the software as a services (SaaS), cloud, data science, and artificial intelligence sectors. Crunchbase Daily. Exclusive Flagship, Orbimed, ARCH, Alta top list of high-performing biotech venture capital firms By Kate Sheridan Reprints Adobe F lagship Pioneering is on track to California-based Interwest Partners focuses on healthcare and IT. Founded in 2009, Capital Factory is a venture capital firm and an accelerator based in Austin, Texas. Since launching its healthcare technology investments in 1993, the group has become one of the industrys top venture capitalists. Since 1996, Alta Partners, a renowned life science venture capital firm, has invested in over 130 businesses. The two main areas for venture capitalist (VC) investment - technology and healthcare - have grown during the COVID-19 pandemic and investors have ample dry Synthetic biology investment set a nearly $8 billion record 16 Best Oklahoma Based Venture Capital Firms of 2021. by Tenner Smith 2 years ago. Asia Pacific ; Morgenthaler VenturesLife Sciences Team, City (cities) where offices are located: Palo Alto, CA; Boston; Boulder, CO, Fund size and status: More than $2.5 billion under management, Current fund: $400 million Fund IX, closed 2008 and used in part for investment in life-sciences companies. The firm seeks to accelerate companies in the software, media and technology sectors in Texas. The curated list of the most valuable private companies in the world |. The overall investment in Biotech firms has grown significantly. See: http://www.sec.gov/Archives/edgar/data/1609495/000160949214000002/xslFormDX01/primary_doc.xml MPM BioVentures was approaching the end of fundraising, according to an unnamed market source, Reuters PE Hub reported on Sept. 18. Venture The firm primarily prefers to invest in the information technology sectors. ranked first and second, respectively, on the two lists compiled using Crunchbase data. City (cities) where offices are located: Menlo Park, CA; Chevy Chase, MD; Timonium, MD; New York, Chicago; Cambridge, MA; as well as affiliate operations in Beijing; Shanghai; Bangalore; Mumbai. Content continues City (cities) where offices are located: San Francisco, Fund size and status: $2 billion under management across eight funds, Current fund: $500 million Alta Partners VIII, a first stage-independent life sciences fund closed 2006, Current biopharma portfolio companies: 7TM Pharma, Ablynx, AcelRx Pharmaceuticals, Achaogen, Aegerion Pharmaceuticals, Aerie Pharmaceuticals, Aerovance, Alba Therapeutics, Allakos, Applied Genetic Technologies, Astex Pharmaceuticals, aTyr Pharma, Azelon Pharmaceuticals, Cara Therapeutics, Ceregene, Cerenis Therapeutics, ChemoCentryx, Chimerix, Corcept Therapeutics, CymaBay Therapeutics, Cytokinetics, DiscoveRx, Esperion Therapeutics, Excaliard Pharmaceuticals, Genedata, Immune Design, Intarcia Therapeutics, Kiadis Pharma, Kite Pharma, Lumena Pharmaceuticals, MacroGenics, Neothetics, Nereus Pharmaceuticals, Pathwork Diagnostics, Portola Pharmaceuticals, Proacta Therapeutics, Prolacta Bioscience, SARcode Bioscience, Scynexis, Silence Therapeutics, Sonexa Therapeutics, Sunesis Pharmaceuticals, Sutro Biopharma, Threshold Pharmaceuticals, Trevena, Veloxis Pharmaceuticals, ViroBay, VitrOmics, Zafgen, ZS Pharma, City (cities) where offices are located: Radford, VA; San Francisco; Palm Beach, FL, Fund size and status: More than $2 billion under management through nine affiliated investment funds, consisting of seven New River Management Funds and two regional funds, Current New River Management Funds: $120 million New River Management VII, closed 2012; $15 million Valleys Ventures, launched 2013 to invest in companies that intend to commence operations in, or are willing to relocate to an area within 100 miles of Montgomery, Roanoke or Botetourt counties of southwestern Virginia, Current biopharma portfolio companies: Agilis, AmpliPhi Biosciences, AveXis, Fibrocell Science, Halozyme Therapeutics, Intrexon, Oragenics, OvaScience, Soligenix, Synthetic Biologics, City (cities) where offices are located: Menlo Park, CA, Fund size and status: More than $2 billion under management in nine funds, Most recent fund: $670 million MDV IX fund, first closed 2007 at $580 million. The Indian startup/ VC ecosystem will truly come of age The release is based on public data and may miss organnizations who are not currently releasing their data. Additionally, Bain Capital Crypto closed a $500 million fund in March 2022, and the firm announced a $2.4 billion Tech Opportunities fund earlier this month. 1. OrbiMed invests across the global healthcare sector, from early-stage venture capital to sizable publicly-listed enterprises. Additionally, Bain Capital Crypto closed a $500 million fund in March 2022, and the firm announced a $2.4 billion Tech Opportunities fund earlier this month. The firm is headquartered in San Francisco, California. Founded in 2018, Cathexis Ventures is a corporate venture arm of Cathexis Holdings headquartered in Houston, Texas. Bill Wood Ventures is a venture capital firm based in Austin, Texas. Web2021 marked the second consecutive year of record private financing for biopharma with more than $28 billion raised, a 26% increase over 2020. Third-ranked Flagship Pioneering, for instance, was driven by just two IPOs in 2021. It has a variety of technologies spanning Biopharma, engineering, food, and other areas. In 1999, Versant Ventures, Inc., a Menlo Park, California-based venture capital company, was founded. Our Standards: The Thomson Reuters Trust Principles. The firm seeks to invest in the business products and services sectors. The FDA needs to add, Experts weigh in on potential health hazards posed by, Experts weigh in on potential health hazards posed by chemicals in Ohio train derailment, How a depression test devised by a Zoloft marketer, How a depression test devised by a Zoloft marketer became a crutch for a failing mental, Targeting cancer: the new frontier of immunotherapy and precision, Targeting cancer: the new frontier of immunotherapy and precision oncology, Following your gut: How scientists are getting closer to, Following your gut: How scientists are getting closer to linking the microbiome and chronic diseases. The firm seeks to invest in the media, software, and healthcare sectors. DCVC, based in Palo Alto, California, invests in what it considers "deep tech," so many of the biotech companies it gets involved with are focused on sequencing, artificial intelligence, and other data-driven approaches to healthcare. (9), Current biopharma portfolio companies: CoMentis, Egalet, Epsilon 3 Bio, FF Pharma, GenSight Biologics, GlycoVaxyn, Levicept, Minerva Neurosciences, Molecular Partners, Novocure, Oncoethix, Sequenta, Versartis, XO1, Year established: 1996; successor to Index Securities, founded 1976, City (cities) where offices are located: Boston; Waltham, MA; San Francisco; Dublin; Also, @dogpatchlabs location in Dublin for biotechnology and technology startups, Fund size and status: About $4 billion under management across seven funds (10), Current fund: $450 million Polaris Venture Partners VII, closed Nov. 24; firm says on its website it continues to invest its sixth fund, $375 million Polaris Venture Partners VI, closed 2010 (10), Current biopharma portfolio companies: 480 Biomedical, Acceleron Pharma, Adimab, Advion, AgBiome, Alector, Alimera Sciences, Arsanis Biosciences, Arsenal Medical, aTyr Pharma, Cerulean Pharma, Editas, Fate Therapeutics, Genocea Biosciences, Hydra Biosciences, Ironwood, Kala Pharmaceuticals, KinDex Pharmaceuticals, Navitor Pharmaceuticals, NextCODE, Ocular Therapeutix, Promedior, Pulmatrix, Receptos, Scholar Rock, Selecta Biosciences, T2 Biosystems, Trevena, Visterra, Xtuit Pharmaceuticals, City (cities) where offices are located: Cambridge, MA; New York; Menlo Park, CA; So Paulo, Brazil; Herzliya Pituach, Israel; Bangalore, India, Fund size and status: More than $4 billion under management across eight funds (11), Current fund: $1.6 billion Bessemer Venture Partners VIII, closed 2011 (11), Current biopharma portfolio companies: Acceleron Pharma, AffyMax, Allena Pharmaceuticals, Cerulean Pharma, Flex Pharma, On-Q-ity, OvaScience, Oxagen, Proteon Therapeutics, Transave Inhalation Biopharmaceuticals, Verastem, City (cities) where offices are located: Cambridge, MA; Palo Alto, CA; Shanghai; London; and Geneva, Fund size and status: $4.2 billion under management across 12 funds. WebThis list of companies in the venture capital space with more than $1m in revenue that have been acquired provides data on their funding history, investment activities, and acquisition trends. Along with conventional medicinal biopharma, the firms portfolio also includes a variety of technologies and online health start-ups. The New York-based OrbiMed Healthcare Fund Management has made various investments in the life sciences sector, including MedTech and Biopharma. Versant, based in San Francisco, has $4.1 billion in assets under management and makes a handful of investments in new companies each year, typically investing $20 million to $30 million, a spokesperson said. The Indian startup/ VC ecosystem will truly come of age Founded in 2013, LiveOak Venture Partners is a venture capital firm headquartered in Austin, Texas. Who has the most invested in funding up-and-coming biotechs? WebThe lifeblood of revolutionary medical technologies is venture funding. Essex Woodlands Health Ventures, City (cities) where offices are located: Palo Alto, CA; Houston; New York; London; Shanghai, Fund size and status: More than $2.5 billion under management across eight funds (4), Current fund: $900 million Fund VIII, closed 2009 (4), Current biopharma portfolio companies: Acura Pharmaceuticals, Biotoscana, Bioventus, Catalyst Biosciences, Chroma Therapeutics, Corium, Curis, Echo Therapeutics, Elusys Therapeutics, Horizon Pharma, IntegenX, LightSciences Oncology, Medicinova, Molecular Partners, Open Monoclonal Technology, Oraya Therapeutics, Revance Therapeutics, Symphogen, Ziopharm Oncology, City (cities) where offices are located: Cambridge, MA; New York; Palo Alto, CA, Fund size and status: $2.6 billion under management across seven funds, Current funds: $450 million Venrock VII, closed July 2014 and intended to invest in technology and healthcare companies; $350 million Venrock VI, closed 2010 (5), Current biopharma portfolio companies: Acceleron Pharma, Achaogen, Anacor Pharmaceuticals, Ariosa Diagnostics, Avalanche Biotech, AVEO Pharmaceuticals, Celladon, Cerulean, Constellation Pharmaceuticals, CymaBay Therapeutics, Fate Therapeutics, Hua Medicine, Infinity Pharmaceuticals, Intarcia Therapeutics, Ironwood Pharma, Juno Therapeutics, QuatRx Pharmaceuticals, Receptos, Vitae Pharmaceuticals, City (cities) where offices are located: Boston (6); South San Francisco, CA; Gainesville, FL; Munich, Fund size and status: More than $2.6 billion committed capital under management across five funds, Current fund: Approximately $300 million MPM BioVentures V L.P., closed 2010 (7), Current biopharma portfolio companies: 23andMe, Amphivena Therapeutics, Anthera Pharmaceuticals, Aratana Therapeutics, Astute Medical, Celladon, Cerecor, Chiasma, Conatus Pharmaceuticals, Epizyme, Iconic Therapeutics, Mitokyne, Proteon Therapeutics, Radius Health, Rhythm Pharmaceuticals, SAI, Selexys Pharmaceuticals, Sideris Pharmaceuticals, Solasia Pharma, Syndax Pharmaceuticals, Theraclone Sciences, True North Therapeutics, Vascular Pharmaceuticals, Verastem, City (cities) where offices are located: Princeton, NJ, and San Diego, Fund size and status: More than $2.7 billion under management across eight funds, Current fund: $500 million Domain Partners VIII, closed 2009, Current biopharma portfolio companies: Achaogen, Achillion Pharmaceuticals, Adynxx, Afferent Pharmaceuticals, Aldeyra Therapeutics, Alimera Sciences, Applied Proteomics, Ariosa Diagnostics, Ascenta Therapeutics, Asmacure, Astute Medical, Atara Biotherapeutics, aTyr Pharma, BioNano Genomics, Cantex Pharmaceuticals, Celator Pharmaceuticals, Clovis Oncology, CoDa Therapeutics, CoLucid Pharmaceuticals, Dicerna Pharmaceuticals, Domain Elite Holdings, Domain Russia Investments, Eddingpharm International Holdings, Epic Sciences, Esperion Therapeutics, Evoke Pharma, Five Prime Therapeutics, IntegenX, Marinus Pharmaceuticals, Meritage Pharma, NovaDigm Therapeutics, Ocera Therapeutics, Oraya Therapeutics, Orexigen Therapeutics, Otonomy, ProteinSimple, Regardo Biosciences, Sera Prognostics, Syndax Pharmaceuticals, Tobira Therapeutics, Tragara Pharmaceuticals, VentiRx Pharmaceuticals, Veracyte, Zogenix, Fund size and status: $2.8 billion under management across 10 funds, Current fund: $650 million InterWest Partners X, closed 2008, Current biopharma portfolio companies: Applied Genetic Technologies (AGTC), Alvine Pharmaceuticals, Arcion Therapeutics, Carbylan Therapeutics, Cebix, Centrexion, Cidara Therapeutics, Drais Pharmaceuticals, Eiger BioPharmaceuticals, Lycera, MacroGenics, Ocera Therapeutics, On Demand Therapeutics, Paratek Pharmaceuticals, PMV Pharma, QuatRx Pharmaceuticals, RadioRx, Tesaro, Trius Therapeutics, USDS, Xenon Pharmaceuticals, City (cities) where offices are located: Cambridge, MA. Research. In addition to the returns from its portfolio companies that went public in 2021, Arch has $1.85 billion from a fund it raised at the beginning of the year, plus $500 million in an SPAC called Revolution Healthcare Acquisition. WebMarket-leading rankings and editorial commentary - see the top law firms & lawyers for Venture capital and emerging companies in United States. 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